CLEVELAND -- Johnny Manziel had scrambled away long before Asdrubal Cabrera came to the plate in the 12th inning. And when Cabrera connected for a three-run homer in the 12th inning, ending a game that took nearly seven hours to play, Indians manager Terry Francona was relieved to be finally leaving the ballpark. "Nice to see anyone come through," Francona said. Cabrera connected for a three-run homer with one out in the 12th, giving Cleveland a 7-4 victory over the Boston Red Sox early Thursday and a three-game sweep of the defending World Series champions. With two runners on and Boston playing five infielders and only two outfielders, Cabrera made the shift moot by driving an 0-1 pitch from Edward Mujica (2-2) into Bostons bullpen as the Indians won their sixth straight overall and ninth in a row at home. Cleveland is an AL-best 21-11 at Progressive Field. Cabrera slid into home plate after his fifth homer and was doused with water by his teammates, who were relieved to finally end a game that didnt finish until 2:02 a.m. The start of the game, originally set for 7:05 p.m., was delayed by rain until 9:33 p.m., cancelling a scheduled ceremonial first pitch by Manziel, the Browns popular rookie quarterback, who flashed his signature "money" gesture when he and his teammates were introduced to the crowd. With practice on Thursday, Manziel ducked out early and was long gone when the game ended with just a few thousand die-hard fans in the seats. The teams each used seven pitchers, who combined to throw 364 pitches. "Regardless of the time, anytime you go 12 innings, losses sting a little bit," Red Sox manager John Farrell said. "We were doing everything we could to extend the ballgame. Guys came out of the bullpen and did a good job. Cabrera just got hold of a breaking ball and put an end to this one." Mujica didnt make any excuses. "That pitch was a big mistake and he hit it out," he said. "I left it over the plate. It was a little crazy, but we had to keep it going however we could." Carlos Carrasco (1-3), the Indians seventh pitcher, worked two innings. The surging Indians have trimmed seven games off first-place Detroits lead in the AL Central in 17 days. Cleveland is within 3 1/2 games and back to .500 for the first time since April 24. David Ortiz homered for the Red Sox, who came in riding a seven-game winning streak but are now headed in the wrong direction. Trailing 4-2 and in danger of leaving town winless, the Red Sox tied it in the seventh inning when they chased Indians starter Corey Kluber on Brock Holts two-run single. Kluber, who was so dominant in May going 4-0 with 60 strikeouts in 43 innings, walked Stephen Drew to start the seventh and Daniel Nava singled. Jackie Bradley Jr. sacrificed and Holt followed with his game-tying base hit to centre. Kluber got a no-decision and remained unbeaten in seven starts since April. He allowed four runs and five hits in 6 1-3 innings. Michael Brantley had three hits off Boston starter Brandon Workman, who pitched while appealing a six-game suspension for throwing at Tampa Bays Evan Longoria last week. Workman gave up three runs in five innings. Ortizs 13th homer gave the Red Sox a 2-1 lead in the sixth. Kluber blanked Boston over the first five innings but opened the sixth by hitting Xander Bogaerts in the right elbow. The right-hander retired Dustin Pedroia on a hard liner to right, but wasnt so fortunate with Ortiz, who ripped a fastball over the fence in right-centre -- a 422-foot shot -- to give the Red Sox their first lead of the series. It didnt last long. The Indians scored three runs in the sixth on an RBI single by Jason Kipnis and another clutch hit by David Murphy, who is batting .383 (18 of 47) with 31 RBIs with runners in scoring position. Brantley picked up his 23rd RBI in his past 32 games in the first with a one-out single to give Cleveland a 1-0 lead. In the fifth, Brantley helped Kluber by making a leaping catch at the left-field wall to rob Bradley of extra bases. NOTES: It was the Indians fifth walk-off win. They are 4-1 in extra inning. ... Red Sox C A.J. Pierzynski was ejected in the sixth by plate umpire Quinn Wolcott. ... Brantley is batting .349 (45 of 129) in 32 games since April 29. ... Indians RHP Danny Salazar was placed on the 7-day DL at Triple-A Columbus with a strained right triceps. Francona doesnt think the injury is serious and expects Salazar, who started Clevelands playoff game last October, to miss "one or two starts." ... Indians RHP Zach McAllisters rehab start with Lake County (A) was rained out and pushed to Thursday. The right-hander, out with a sore lower back, is expected make a second start in the minors. 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Kobe Bryant Shoes Sell .ca Fantasy Editor Scott Cullen, NFL Editor Ben Fisher, and Isaac Owusu discuss three hot fantasy football topics.Pittsburgh, PA (SportsNetwork.com) - Blake Comeau and Kris Letang posted early scores, while Rob Klinkhammer provided a late tally as Pittsburgh turned away Calgary, 3-1, at CONSOL Energy Center. Marc-Andre Fleury made 26 saves for the Penguins, who won for the sixth time in their last nine and extended their lead over the idle Islanders in the Metropolitan Division to three points. Great job by them blocking shots, Fleury said of his defensemen and penalty killers, who kept Calgary scoreless in five chances. Keeping them to the outside and out from in front of the net. Very solid night. They won without the services of team captain Sidney Crosby, who was ruled out for the next two games with an unknown medical diagnosis which was not suspected to be the mumps. Crosby did appear after a Friday practice session with one side of his upper jaw swollen, and was kept out of action as a precaution. Johnny Gaudreau picked up the lone goal for the Flames, who lost their fourth straight contest. Jonas Hiller made just 19 saves in the setback. The hosts couldnt give themselves enough breathing room until 2:47 remained in regulation, as Klinkhammer picked up his first goal with the Pens by redirecting a Steve Downie pass home from the slot for a 3-1 advantage. It takes some time, Klinkhammer said. One or two practices, so its good. Its a step in the right direction. The more ice I get with these guys, the better its going to feel. Hilleer was pulled for an extra skater after the ensuing faceoff but the visitors failed to get any closer.dddddddddddd Pittsburgh struck twice in the games first five minutes, with Comeau converting an Evgeni Malkin pass at 48 seconds followed by Letangs redirection of a Simon Despres offering at 4:43 during a 4-on-4 situation. Gaudreau got one back for the Flames at 12:15, following up a Markus Granlund rebound and scoring from the right side. Hiller halted 11 shots and Fleury six in a scoreless but spirited second period. I think in the third period, we needed to play more in their zone, get more guys in front of the net and go to the dirty areas, Flames forward Paul Byron said. It looks like other teams are scoring those goals right in the paint and were not getting enough of those. Game Notes The Pens welcomed back forward Patric Hornqvist after a two-game absence due to an undisclosed injury and Letang after five games with a groin issue ... All nine of Comeaus goals have been scored at home this season ... Flames defenseman Ladislav Smid (upper-body) left the game in the second period and did not return ... Klinkhammer totaled three goals in 19 games with the Coyotes before being dealt to Pittsburgh ... Calgarys dynamic defensive duo of Dennis Wideman and Mark Giordano were held to a combined two shots on goal and a combined minus-2. ' ' '